Biomimetic route to hybrid nano-Composite scaffold for tissue engineering

Nayar, S and Sinha, Arvind (2007) Biomimetic route to hybrid nano-Composite scaffold for tissue engineering. In: Nanoscience and Nanotechnology Initiative (NSTI), 21-23 February, 2007, Katriya Hotel & Towers, Hyderabad.



Hydroxyapatite-poly(vinyl) alcohol-protein composites have been prepared by a biomimetic route at ambient conditions, aged for a fortnight at 30±2°C and given a shape in the form of blocks by thermal cycling. The structural characterizations reveal a good control over the morphology mainly the size and shape of the particles. Initial mechanical studies are very encouraging. Three biocompatibility tests, i.e., hemocompatibility, cell adhesion, and toxicity have been done from Shree Chitra Tirunal, Trivandrum and the results qualify their standards. Samples are being sent for more biocompatibility tests. Optimization of the blocks in terms of hydroxyapatite and polymer composition w.r.t the applications and its affect on the mechanical strength have been initiated. Rapid prototyping and a β-tricalcium – hydroxyapatite combination in composites are in the offing.

Item Type:Conference or Workshop Item (Poster)
Official URL/DOI:
Uncontrolled Keywords:nano-Composites, Biomimetics, Hydroxyapatite
Divisions:Material Science and Technology
ID Code:6490
Deposited By:Dr. A K Sahu
Deposited On:25 Mar 2013 12:15
Last Modified:25 Mar 2013 12:15
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