Topographical heterogeneity in transparent PVA hydrogels studied by AFM

Pramanick, A K and Gupta, Siddhi and Mishra, T and Sinha, Arvind (2012) Topographical heterogeneity in transparent PVA hydrogels studied by AFM. Materials Science and Engineering C, 32 (2). pp. 222-227.

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Physically crosslinked poly (vinyl alcohol) (PVA) hydrogels have a wide range of biomedical applications. Transparent and stable PVA hydrogels synthesized by freeze-thawing method are potential candidates to be used as tissue engineering scaffolds provided they exhibit suitable topographical roughness and surface energy. The effect of processing parameters i.e., polymer concentration and number of freeze-thaw cycles on the resulting topography of the freeze-thawed transparent hydrogels has been studied and quantified using non-contact mode of an atomic force microscope (AFM) and image analysis. Simultaneously captured phase contrast images have revealed significant information about morphological changes in the topographical features and crystallinity of the hydrogels. Topographical roughness was found to decrease as a function of number of freeze-thaw cycles. © 2011 Elsevier B.V. All rights reserved.

Item Type:Article
Official URL/DOI:
Uncontrolled Keywords:Atomic force microscopy; PVA Hydrogels; Topography; Transparent
Divisions:Corrosion and Surface Engineering
Material Science and Technology
ID Code:4721
Deposited By:Dr. A K Sahu
Deposited On:07 Feb 2012 10:30
Last Modified:07 Feb 2012 10:30
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