Synthesis of fully interconnected multiporous hydroxyapatite block for orthopedic application

Sarkar, C and Sinha, Arvind (2020) Synthesis of fully interconnected multiporous hydroxyapatite block for orthopedic application. Journal of Metallurgy and Materials Science, 62(3-4) . pp. 21-29.

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Abstract

In the present work, three dimensional multiporous hydroxyapatite block has been synthesized by a novel process which comprises of two steps. At first, three dimensional polymer-hydroxyapatite nanocomposite was synthesized by mimicking matrix mediated in situ biomineralization process. Second is sintering step where synthesized polymer-hydroxyapatite composite was sintered at 1200°C under atmospheric pressure. After sintering, a structurally stable fully interconnected multiporous hydroxyapatite block was obtained. Detailed structural and chemical characterization revealed the role of polymer matrix in the formation of three dimensional multiporous hydroxyapatite block. Cytocompatibility of sintered hydroxyapatite block was evaluated by MTT assay and cell adhesion test. Results evidenced the non-toxic nature of sintered hydroxyapatite block.

Item Type:Article
Official URL/DOI:https://doi.org/http://www.indianjournals.com/ijor...
Uncontrolled Keywords:Hydroxyapatite; Three dimensional; Biomimetic; Block; Sintering
Divisions:Material Science and Technology
ID Code:8317
Deposited By:Sahu A K
Deposited On:03 Mar 2021 12:39
Last Modified:03 Mar 2021 12:39
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