Guha, Avijit and Singh, Sashi and Kumaresan, R and Nayar, S and Sinha, Arvind (2009) Mesenchymal cell response to nanosized biphasic calcium phosphate composites. Colloids and Surfaces B: Biointerfaces, 73 (1). pp. 146-151.
![[img]](/style/images/fileicons/application_pdf.png) | PDF Restricted to NML users only. Others may use -> 1416Kb |
Abstract
Biphasic calcium phosphate nanoparticles comprising both hydroxyapatite (HA) and β polymorph of tricalcium phosphate (β-TCP) have been synthesized together by a polymer matrix mediated process. The process, based on in situ mineralization of poly (vinyl alcohol), exerts a good control over the morphological features of biphasic nanoparticles. By controlling the reaction chemistry (Ca:P ratios), nanobioceramic particles having three different HA/β-TCP ratios of 50:50, 55:45 and 60:40 respectively. As the two constituents of biphasic system (HA and β-TCP) facilitate series of signaling cascades in osteoblast division and differentiation, the adhesion and differentiation properties of mesenchymal cells (MSCs) derived from bone marrow has been studied.
| Item Type: | Article |
|---|---|
| Official URL/DOI: | http://dx.doi.org/10.1016/j.colsurfb.2009.05.009 |
| Uncontrolled Keywords: | Nanocomposites; Biphasic calcium phosphate; Biomimetic; Mesenchymal stem cells |
| Divisions: | Material Science and Technology |
| ID Code: | 664 |
| Deposited By: | Sahu A K |
| Deposited On: | 02 Jun 2010 12:13 |
| Last Modified: | 21 Jul 2010 20:47 |
| Related URLs: |
Repository Staff Only: item control page
