Sinha, Arvind and Guha, Avijit (2009) Biomimetic patterning of polymer hydrogels with hydroxyapatite nanoparticles. Materials Science and Engineering: C, 29 (4). pp. 1330-1333.
PDF 626Kb |
Abstract
We report here an in situ process to produce nano-composite polymer hydrogels having surfaces patterned with hydroxyapatite (HA) nanoparticles (100 nm). Poly (vinyl alcohol) (PVA) has been used as a hydrogel forming medium. A three step process, comprising precipitation of HA nanoparticles in presence of PVA molecules and freeze thawing of obtained PVA-HA emulsion, followed by critical point drying, has been devised to produce three dimensional nanocomposite hydrogels. Interaction of Ca2+ with oxygen atoms of PVA and the hydrogen bonding characteristic of the polymer have been exploited to have controlled size distribution of HA in a continuous and macroporous network of PVA. A systematic variation in the polymer concentration could be correlated with microstructural features of the hydrogel.
Item Type: | Article |
---|---|
Official URL/DOI: | http://dx.doi.org/10.1016/j.msec.2008.10.024 |
Uncontrolled Keywords: | Biomimetic; Tissue Engineering; Hydroxyapatite; Poly (vinyl alcohol); Scaffolds |
Divisions: | Material Science and Technology |
ID Code: | 26 |
Deposited By: | Dr. A K Sahu |
Deposited On: | 22 Sep 2009 15:59 |
Last Modified: | 09 Feb 2012 13:11 |
Related URLs: |
Repository Staff Only: item control page